This article is a systematic review composed of 38 studies including about 52,000 patients. It focuses on the factors that lead to poor compliance among patients with schizophrenia and bipolar disorder. One of the most prominent factors was alcohol dependence, which made it very unlikely that the patient would adhere to treatment. Another important factor was ethnicity, with Hispanics and African-American patients having the poorest compliance. African-Americans were more likely to have negative perceptions regarding the medications– they were scared of getting addicted or the idea that if they take medication they have an illness. Furthermore, younger age of onset, low socioeconomic status, severe depressive symptoms, and poor social support were more likely to result in poor outcomes. The article advised on certain measures that helped increase compliance. The article advised that providers should thoroughly educate the patient on the medication and its importance as well as the patient’s family. Furthermore, a strong relationship between patient and provider, with the patient having a role in his or her own care, was more likely to be successful. Providers should also reduce the number of drugs prescribed and frequency of doses to make it easier for the patients. Lastly, it is important to consider the price of certain medications as well as arranging transportation for the patient, two significant financial barriers that limit compliance. 

 

Antipsychotic Adherence_Garcia